A new Leica cryomicrotome makes possible the sectioning of soft material for TEM analysis. The Leica Ultra Cryo UC7 is a state-of-the-art diamond-knife instrument operating anywhere between 77°K and room temperature. Accessories include a trimming mill and a glass knife maker.
Materials suitable for microtome slicing include polymer beads, carbon nanotubes, electro-spun fibers, and soft metals.
More expertise in tissue sectioning and staining can be found at the Yale Medical School TEM facility.